Genetic Freedom: Virus Mutating, Borders Closing

Several European countries closed their borders to Great Britain on 12/20/2020, because the SARS-Cov2 virus mutated in a form which is “70% more transmissible” say British authorities… which themselves applied a ferocious lockdown inside the UK. Now this was fully predictable.

In related news, analysis of old Viking remains seems to have revealed that they had smallpox (“variola”) but of a less lethal sort… a millennium or so, ago. Vikings are prefered, not because forensic doctors are systemic racist, but because corpses are best conserved in a cold climate. So smallpox adapted by becoming more lethal. Why? asked a lawyer friend of mine. Simple: as there are many people, a virus can afford to kill its host. And the more people, the more people can the virus kill, and thrive. A giant human population creates a giant ecological niche for lethal microbes.

One could say that virus and other lethal microbes are Gaia’s reaction to the human infection, my lawyer friend pointed out. Indeed. But the human infection is smart.

RNA vaccines are a GIANT plus. They were initially devised for cancer. Little advertised, a RNA vaccine ELIMINATED this extremely lethal RNA virus EBOLA in 2020 from the Congo (RDC). It was a minus 80 C vaccine… a little complex to transport in the wild tracks of the rainforest…

If RNA vaccines are made to work against cancer, they will be a testimony of the goodness of venture capital applied to science… There has been a tremendous ramp up in the venture capital and associate Intellectual Property and legal areas in the last ten years. The idea with cancer is that each individual cancer is unique (same for antibodies cocktails against COVID). Once specific surface proteins are identified with their messenger RNA, one envelops the whole thing with an irritant (“adjuvant”), and… voila! The immune system gets furious against the adjuvant and exterminate anything associated to it… in particular what is covered with the characteristic protein the mRNA coded for… Messenger RNA vaccines are eminently adjustable, and following the mutations of the virus should not be a problem… Once the present stock of vaccines is injected…

Universe, here we come. Gaia, your meek viruses shall not stop us. Perversely, indeed, they will help us vanquish cancer, and acquire GENETIC FREEDOM.

Mini-brain’ bioengineered from human stem cells. The ball is about one third of a millimeter and contains about 30,000 neuron-like cells. The cell nuclei are blue. The SARS-CoV-2 virus is stained red, indicating that a small fraction of brain cells carries a large number of virus particles. This means that virus has multiplied enormously in infected cells.

Patrice Ayme

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6 Responses to “Genetic Freedom: Virus Mutating, Borders Closing”

  1. benign Says:

    Sounding a little transhumanist there, Patrice.

    Why do we need an mRNA “vaccine” anyway (it’s really a therapeutic as far as I can tell)? If the SARS-CoV-2 genome has been sequenced (often, allegedly), why not use a denatured bit of it, and produce using PCR?



    • Patrice Ayme Says:

      I don’t have a PhD in genetic engineering… But: Polymerase Chain Reaction (PCR) rapidly makes millions to billions of copies of a specific DNA sample, allowing to take a very small sample of DNA and amplify it to a large enough amount to study in detail. However, coronaviruses contain a positive-sense, single-stranded RNA genome… NOT DNA!

      One has to code for coating… The two MRNA vaccines code for the protein the spikes are made of, the spikes the immune system can see…


    • Patrice Ayme Says:

      Indeed, I am definitely transwhatever… Since ever… 😉


  2. Gmax Says:

    Very interesting as usual. The virus is mutating to spread faster? Will that nightmare ever end? Can they change the vaccines fast enough?


    • Patrice Ayme Says:

      Yes, as I said. First a mutation would have to change the spikes, and apparently they do, all the time… But then if the spikes protein change SIGNIFICANTLY, so can the mRNA vaccine… The basic machinery of the vaccine would stay the same. That’s the big advantage on more traditional approaches… The Sanofi-Pasteur vaccine a traditional modification of the measles, just failed… Not immunizing enough…


  3. Patrice Ayme Says:

    [Answer to private correspondence wondering whether i got some details right]

    Thanks. The Lipid NanoParticles (LNP) vehicles used to deliver the RNA probably have some adjuvant effect. So does the alien mRNA itself (which has been supposedly “tempered down”). If it talks like a duck, walks like a duck, and flies like a duck, we may as well call it an adjuvant…

    Moderna boasts that, having already developed ten RNA vaccines, their LNPs are less temperature sensitive.

    I mentioned the Ebola vaccine because of the very low temperatures. BioNtech/Pfizer and Moderna vaccines are the first true RNA vaccines deployed, and here to stay as the failure of some of the other vaccines indicates.


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